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Is CT perfusion helpful in the treatment allocation of patients with acute ischemic stroke? An expert opinion analysis E. Schirinzi, L. Strada, J.Y. Streifler, B. Del Sette, A. Castaldi, M. Del Sette |
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Summary |
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Proceedings SNO |
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Background:
Intravenous tPA is the standard treatment for acute ischemic stroke
within 4.5 hours of symptom onset. Neruradiological selection is
currently based upon non-contrast-enhanced cerebral CT (NCCT). Aim of
our study was to verify, in an “expert-opinion setting”, the
possible usefulness of CT perfusion (CTP) in decision-making toward i.v.
thrombolysis. Patients
and method: One hundred and three consecutive patients with acute
ischemic stroke who underwent NCCT and CTP were re-evaluated by an
expert in cerebrovascular disease, to verify if adding CTP information
would have changed expert’s opinion. Results:
After CTP, a definitive decision was made for 20 more patients, changing
the proportion of patients candidate to i.v. tPA from 44% to 51%, and
reducing uncertainty from 29% to 10%. CTP results were useful in milder
stroke (p = 0.01). Conclusions:
In a “real world” setting, CT perfusion could be useful for clinical
decision, in particular for milder stroke. |
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Articles from "Proceedings" are provided here courtesy of |
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Proceedings SNO - ISBN 978-88-8041 - Copyright © 2017 SNO & new MAGAZINE s.r.l. - Italy |
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