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Proceedings SNO “Percorsi clinici in Neuroscienze”

DISCUSSIONE 2. McCarthy DJ, Tonetti DA, Stone J, Starke RM, Narayanan
S, Lang MJ, Jadhav AP, Gross BA. More expansive hori-
I recenti Trial (Dawn e Defuse3) dimostrano il bene- zons: a review of endovascular therapy for patients with low
NIHSS scores. J Neurointerv Surg 2021; 13 (2): 146-151.
ficio della terapia endovascolare nelle prime 12/24
3. Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik
ore in pazienti con piccolo core ischemico; altrettan-
RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel
to positivi sono i risultati nei pazienti con basso
RA, Sila CA, Hassan AE, Millan M, Levy EI, Mitchell P,
NHISS ed occlusione di un grosso vaso trattati per Chen M, English JD, Shah QA, Silver FL, Pereira VM,
via endovascolare. Mehta BP, Baxter BW, Abraham MG, Cardona P,
In conclusione, nei casi descritti un imaging adeguato Veznedaroglu E, Hellinger FR, Feng L, Kirmani JF,
(anche perfusionale) e un inquadramento clinico det- Lopes DK, Jankowitz BT, Frankel MR, Costalat V, Vora
NA, Yoo AJ, Malik AM, Furlan AJ, Rubiera M, Aghae-
tagliato costituiscono strumenti necessari per una otti-
brahim A, Olivot JM, Tekle WG, Shields R, Graves T,
male gestione di questo gruppo di pazienti.
Lewis RJ, Smith WS, Liebeskind DS, Saver JL, Jovin
TG; DAWN Trial Investigators. Thrombectomy 6 to 24
hours after stroke with a mismatch between deficit and in-
farct. N Engl J Med 2018; 378 (1): 11-21.
BIBLIOGRAFIA
4. Shang X, Lin M, Zhang S, Li S, Guo Y, Wang W, Zhang
1. Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, M, Wan Y, Zhou Z, Zi W, Liu X. Clinical outcomes of en-
Ortega-Gutierrez S, McTaggart RA, Torbey MT, Kim- dovascular treatment within 24 hours in patients with
Tenser M, Leslie-Mazwi T, Sarraj A, Kasner SE, Ansari SA, mild ischemic stroke and perfusion imaging selection.
AJNR Am J Neuroradiol 2018; 39 (6): 1083-1087.
Yeatts SD, Hamilton S, Mlynash M, Heit JJ, Zaharchuk G,
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R, Lavori PW, Broderick JP, Lansberg MG; DEFUSE 3 vascular mechanical thrombectomy in large-vessel occlu-
Investigators. Thrombectomy for stroke at 6 to 16 hours sion ischemic stroke presenting with low National In-
with selection by perfusion imaging. N Engl J Med 2018; stitutes of Health Stroke Scale: systematic review and
378 (8): 708-718. meta-analysis”. World Neurosurg 2019; 125: 542.

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