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Proceedings SNO                                                    “LXI Congresso Nazionale SNO”



                                                               tory of human anatomy both conceptually and aesthet-
                                                               ically, the first real treatise on human anatomy written
                                                               in a scientific way, which emphasizes the importance
                                                               of dissection. The plates of the seventh book from the
                                                               Fabrica show the first realistic rendering of the brain.
                                                               The beautiful engravings by Vesalius show us an illu-
                                                               stration of the lateral surface of the brain, he designed
                                                               the gyri and the convolutions of the brain depicted
                                                               completely randomly. Vesalius followed Galen in stres-
                                                               sing the protective function of the meninges, he did not
                                                               recognize the arachnoid membrane as a separate enti-
                                                               ty but mentioned the pia mater as a mold of the brain
                                                               protecting it from the rough dura mater (Figure 4).
                                                               COSTANTINUS VAROLIUS (1543-1575), a physician from
                                                               Vesalius’ school, confirmed Vesalius’ findings on me-
                                                               ninges and achieved celebrity for his idea to examine
                                                               the inferior view of the brain (Figure 5).
                                                               GIROLAMO FABRICI D’ACQUAPENDENTE (1533-1619) in
                                                               1600 had amassed more than 300 painting that togeth-
                                                               er made the Tabulae Pictae, a document of exception-
                                                               al scientific value, thanks to the unprecedented realism
                                                               given to the anatomical structures by the innovative
              Figura 3. From Dryander, Anatomiae, 1537.
                                                               use of colors. It is thanks to Fabrici for having first af-
                                                               firmed the importance of the use of color in anatomi-
                                                               cal images, a reference book containing illustrations,
              main source of scientific authority, affirmed a “mod-  hand-painted with natural colors, with details of the
              ern” anatomy sustained by manual virtuosity. His De  human body. Only the illustrations (over 200), paint-
              Humani Corporis Fabrica Libri Septem (1543) is a  ed in oil on paper, whose dark background helps to
              perfect synthesis of scientific rigor and artistic beauty,  suggest a three-dimensional effect. The third volume
              which remains the most representative book in the his-  of these Tabulae entitled De Anatomia Capitis Cerebri






























              Figure 4. From Vesalio, De humani corporis fabrica libri sep-  Figure 5. From Varolius, De nervis Opticis, 1573.
              tem, 1543.



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